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L-arginine monohydrochloride

CAS No. 1119-34-2

L-arginine monohydrochloride ( L-(+)-Arginine | NSC 7914 | NSC 203450 )

产品货号. M10428 CAS No. 1119-34-2

L-精氨酸是合成一氧化氮的氮供体,一氧化氮是镰状细胞危象时期缺乏的有效血管扩张剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
1G ¥389 有现货

生物学信息

  • 产品名称
    L-arginine monohydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    L-精氨酸是合成一氧化氮的氮供体,一氧化氮是镰状细胞危象时期缺乏的有效血管扩张剂。
  • 产品描述
    L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.(In Vitro):Arginine is an α-amino acid. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice.
  • 体外实验
    Arginine is an α-amino acid. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice.
  • 体内实验
    ——
  • 同义词
    L-(+)-Arginine | NSC 7914 | NSC 203450
  • 通路
    Immunology/Inflammation
  • 靶点
    Amino Acids and Derivatives
  • 受体
    Amino Acids and Derivatives
  • 研究领域
    Other Indications
  • 适应症
    ——

化学信息

  • CAS Number
    1119-34-2
  • 分子量
    210.66
  • 分子式
    C6H15ClN4O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    Water: 42 mg/mL (199.37 mM)
  • SMILES
    N[C@@H](CCCNC(N)=N)C(O)=O.[H]Cl
  • 化学全称
    L-arginine hydrochloride

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Morris CR, et al. Am J Respir Crit Care Med, 2003, 168(1), 63-69.
产品手册
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